Cawello W
Schwarz Pharma AG, Monheim am Rhein, Germany.
Int J Clin Pharmacol Ther. 1997 Oct;35(10):414-7.
The present article gives an introduction to the correlation between drug transports and drug action in a body system. Direct linked model uses the law of mass action to describe the PK/PD modelling. More complex models like indirect linked models are discussed.
本文介绍了人体系统中药物转运与药物作用之间的相关性。直接联系模型使用质量作用定律来描述药代动力学/药效学建模。还讨论了更复杂的模型,如间接联系模型。