Kim H J, Hwang E G
Department of Diagnostic Radiology and Institute of Cancer Research, Gyeongsang National University Hospital, South Korea.
Auris Nasus Larynx. 1997 Oct;24(4):423-7. doi: 10.1016/s0385-8146(97)00018-7.
Small cell carcinoma of the larynx is an uncommon epithelial tumor, which is the most aggressive subtype of neuroendocrine carcinomas. Because of its nonspecific clinical and radiological manifestations, the diagnosis of small cell carcinoma of the larynx is essentially based on the light microscopic examination aided by electron microscopy or immunohistochemical staining. We report a case of supraglottic small cell carcinoma accompanied by large bilateral cervical lymph node metastasis ocurring in a 70-year-old man. On CT scans, no area of low attenuation indicating necrosis was demonstrated within such large metastatic lymph nodes. We suggest that small cell carcinoma of the larynx should be included in the diagnostic considerations when a laryngeal mass is accompanied by large cervical lymph nodes without necrosis shown by CT.
喉小细胞癌是一种罕见的上皮性肿瘤，是神经内分泌癌中侵袭性最强的亚型。由于其临床和影像学表现不具有特异性，喉小细胞癌的诊断主要基于光镜检查，并辅以电镜或免疫组化染色。我们报告一例发生在一名70岁男性的声门上型小细胞癌，伴有双侧颈部大淋巴结转移。在CT扫描中，如此大的转移性淋巴结内未显示出提示坏死的低密度区域。我们建议，当喉部肿物伴有CT显示无坏死的颈部大淋巴结时，应将喉小细胞癌纳入诊断考虑范围。
