西格玛E是大肠杆菌中的一种必需的西格玛因子。
SigmaE is an essential sigma factor in Escherichia coli.
作者信息
De Las Peñas A, Connolly L, Gross C A
机构信息
Department of Bacteriology, University of Wisconsin-Madison, 53706, USA.
出版信息
J Bacteriol. 1997 Nov;179(21):6862-4. doi: 10.1128/jb.179.21.6862-6864.1997.
Abstract
SigmaE is an alternative sigma factor that controls the extracytoplasmic stress response in Escherichia coli. SigmaE is essential at high temperatures but was previously thought to be nonessential at temperatures below 37 degrees C. We present evidence that sigmaE is an essential sigma factor at all temperatures. Cells lacking sigmaE are able to grow at low temperatures because of the presence of a frequently arising, unlinked suppressor mutation.
摘要
西格玛E是一种替代西格玛因子，可控制大肠杆菌中的胞外应激反应。西格玛E在高温下是必需的，但以前认为在低于37摄氏度的温度下是非必需的。我们提供的证据表明，西格玛E在所有温度下都是必需的西格玛因子。缺乏西格玛E的细胞由于存在频繁出现的、不连锁的抑制突变而能够在低温下生长。
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