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内源性——神经症性区分作为抗抑郁药物反应的预测指标。

The endogenous--neurotic distinction as a predictor of response to antidepressant drugs.

作者信息

Raskin A, Crook T H

出版信息

Psychol Med. 1976 Feb;6(1):59-70. doi: 10.1017/s0033291700007509.

DOI:10.1017/s0033291700007509
PMID:935298
Abstract

An inverse factor analysis of 880 depressed inpatients on 33 endogenous-neurotic variables yielded four patient types. Type 3 resembled the endogenous depressions and Type 2 the neurotic depressions. Type 3 patients responded well to both imipramine and chlorpromazine and did poorly on a placebo. Type 2 patients showed the greatest overall improvement at three weeks irrespective of treatment received, including a placebo.

摘要

对880名抑郁症住院患者的33个内源性-神经症变量进行反向因子分析,得出了四种患者类型。3型类似于内源性抑郁症,2型类似于神经症性抑郁症。3型患者对丙咪嗪和氯丙嗪反应良好,而对安慰剂反应不佳。2型患者无论接受何种治疗,包括安慰剂,在三周时总体改善最为明显。

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Prediction of short-term outcome of neurotic-depressive inpatients. Results of an empirical study of 134 inpatients.
神经症性抑郁住院患者短期预后的预测。对134名住院患者的实证研究结果。
Eur Arch Psychiatry Clin Neurosci. 1993;242(5):301-9. doi: 10.1007/BF02190390.
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The place of anxiety in depressive symptomatology.焦虑在抑郁症状学中的地位。
Br J Clin Pharmacol. 1983;15 Suppl 2(Suppl 2):171S-179S. doi: 10.1111/j.1365-2125.1983.tb05863.x.
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Prediction of therapeutic response in acute treatment with antidepressants. Results of an empirical study involving 159 endogenous depressive inpatients.抗抑郁药急性治疗中治疗反应的预测。一项涉及159名内源性抑郁症住院患者的实证研究结果。
Eur Arch Psychiatry Neurol Sci. 1987;236(6):349-57. doi: 10.1007/BF00377424.
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Are we as depressed as we think we are?我们真的如自己所想的那般抑郁吗?
Ulster Med J. 1977;46(2):105-12.
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Subtypes of depression--diagnosis and medical management.抑郁症的亚型——诊断与药物治疗
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