Raskin A, Crook T H
Psychol Med. 1976 Feb;6(1):59-70. doi: 10.1017/s0033291700007509.
An inverse factor analysis of 880 depressed inpatients on 33 endogenous-neurotic variables yielded four patient types. Type 3 resembled the endogenous depressions and Type 2 the neurotic depressions. Type 3 patients responded well to both imipramine and chlorpromazine and did poorly on a placebo. Type 2 patients showed the greatest overall improvement at three weeks irrespective of treatment received, including a placebo.
对880名抑郁症住院患者的33个内源性-神经症变量进行反向因子分析,得出了四种患者类型。3型类似于内源性抑郁症,2型类似于神经症性抑郁症。3型患者对丙咪嗪和氯丙嗪反应良好,而对安慰剂反应不佳。2型患者无论接受何种治疗,包括安慰剂,在三周时总体改善最为明显。