猪痢疾蛇形螺旋体溶血素的溶菌活性分析。
Analysis of the lytic activity of the Serpulina hyodysenteriae hemolysin.
作者信息
Hyatt D R, Joens L A
机构信息
Department of Veterinary Science, The University of Arizona, Tucson 85721, USA.
出版信息
Infect Immun. 1997 Nov;65(11):4877-9. doi: 10.1128/iai.65.11.4877-4879.1997.
Abstract
The hemolysins of Serpulina hyodysenteriae are active at 27 to 40 degrees C and pH 3 to 9 and are unaffected by enzymatic inhibitors. Pore formation was demonstrated by the inhibition of hemolysis with molecules of 2.0 to 2.3 nm in diameter and the release of 86rubidium from erythrocytes without hemoglobin release after exposure to native hemolysin.
摘要
猪痢疾蛇形螺旋体的溶血素在27至40摄氏度及pH值3至9时具有活性，且不受酶抑制剂的影响。通过用直径为2.0至2.3纳米的分子抑制溶血以及在暴露于天然溶血素后红细胞释放86铷而不释放血红蛋白，证明了孔的形成。
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