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人体心脏、脾脏和肝脏中磁性物质的分析。

Analysis of magnetic material in the human heart, spleen and liver.

作者信息

Grassi-Schultheiss P P, Heller F, Dobson J

机构信息

Swiss Federal Institute of Technology, ETH-Hönggerberg, Zürich, Switzerland.

出版信息

Biometals. 1997 Oct;10(4):351-5. doi: 10.1023/a:1018340920329.

DOI:10.1023/a:1018340920329
PMID:9353885
Abstract

Isothermal remanent magnetization (IRM) acquisition and alternating field (A.F.) demagnetization analyses were performed on human heart, spleen and liver samples resected from cadavers. The magnetic properties of the samples were measured both at 77K and at 273K. A.F. demagnetization was performed at 273K. Results from the analyses of the tissue indicate the presence of ferromagnetic, fine-grained, magnetically interacting particles which, due primarily to magnetic properties, are thought to be magnetite and/or maghemite. The presence of superparamagnetic particles can be inferred from the increase in saturation IRM values when measured at 77K compared with measurements at 273K and the decay of remanent magnetization upon warming from 77K. The concentration of magnetic material (assuming it is magnetite or maghemite) in the samples varies from 13.7 ng g-1 to 343 ng g-1, with the heart tissue generally having the highest concentration. The presence of magnetic material in these organs may have implications for the function of biogenic magnetite in the human body.

摘要

对从尸体切除的人体心脏、脾脏和肝脏样本进行了等温剩磁(IRM)采集和交变磁场(A.F.)退磁分析。在77K和273K下测量了样本的磁性。在273K下进行了A.F.退磁。组织分析结果表明存在铁磁性、细颗粒、磁相互作用的颗粒,主要由于磁性特性,这些颗粒被认为是磁铁矿和/或磁赤铁矿。从77K测量时饱和IRM值与273K测量值相比的增加以及从77K升温时剩磁的衰减可以推断出超顺磁性颗粒的存在。样本中磁性物质(假设为磁铁矿或磁赤铁矿)的浓度在13.7 ng g-1至343 ng g-1之间变化,心脏组织的浓度通常最高。这些器官中磁性物质的存在可能对人体中生物源磁铁矿的功能有影响。

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