Franke U, Jurmann M J, Uthoff K, Köhler A, Jurmann B, Wahlers T, Borst H G
Division of Thoracic and Cardiovascular Surgery, Radiological Center, Hannover Medical School, Germany.
Ann Thorac Surg. 1997 Oct;64(4):1096-8. doi: 10.1016/s0003-4975(97)00802-3.
Long-term changes in knitted Dacron grafts inserted into the infrarenal aorta have been addressed by a number of studies indicating their potential for postoperative dilatation. In contrast, the behavior of woven, collagen-presealed, double-velour Dacron grafts used to replace the thoracic aorta is not known.
Forty-five patients were examined at a mean of 32.4 +/- 14.8 months after insertion of woven, collagen-coated, Dacron double-velour prostheses (Meadox woven with Hemashield, Meadox, Oakland, NJ) in the thoracic position under highly standardized conditions using spiral computed tomography.
Compared with a manufactured diameter of 26 mm, all grafts showed an increase of 1 to 5 mm (mean, 3.0 +/- 1.2 mm [11.6% +/- 4.4%]; p < 0.0001) with greater enlargement of the ascending than of the descending aortic portions (p = not significant). A further statistically significant progressive dilatation failed to occur. Degenerative changes, including false aneurysm formation, could be excluded.
Woven, collagen-coated Dacron prostheses are considered a safe replacement material for the thoracic aorta.
多项研究探讨了植入肾下腹主动脉的针织涤纶移植物的长期变化，表明其术后有扩张的可能性。相比之下，用于替换胸主动脉的编织、胶原预封、双面绒涤纶移植物的性能尚不清楚。
在高度标准化条件下，对45例患者进行了螺旋计算机断层扫描检查，这些患者在胸段植入编织、胶原涂层的涤纶双面绒假体（Meadox公司生产的Hemashield编织物，Meadox公司，新泽西州奥克兰）后平均32.4±14.8个月。
与制造直径26mm相比，所有移植物均增大1至5mm（平均3.0±1.2mm[11.6%±4.4%]；p<0.0001），升主动脉部分比降主动脉部分增大更明显（p=无显著性差异）。未出现进一步具有统计学意义的渐进性扩张。可排除包括假性动脉瘤形成在内的退行性改变。
编织、胶原涂层的涤纶假体被认为是胸主动脉的安全替代材料。
