Morley J E, Kaiser F E, Sih R, Hajjar R, Perry H M
Geriatric Research Education and Clinical Center, St. Louis VAMC, and Division of Geriatric Medicine, St. Louis University Medical School, St. Louis, Missouri, USA.
Clin Geriatr Med. 1997 Nov;13(4):685-95.
Although estrogen replacement therapy has become well established in the management of postmenopausal women, most physicians pay much less attention to the testosterone status of their older male patients. There is now increasing evidence that testosterone deficiency-Low Testosterone Syndrome-occurs in older men and is associated with decreased muscle strength and bone density, as well as memory problems. This article reviews the evidence for the existence of Low Testosterone Syndrome, often characterized as the male menopause or viropause, and the emerging evidence that testosterone therapy may ameliorate some of the symptoms and signs of frailty in men beyond 50 years of age.
尽管雌激素替代疗法在绝经后女性的治疗中已得到广泛应用，但大多数医生对老年男性患者的睾酮水平关注较少。现在越来越多的证据表明，睾酮缺乏——低睾酮综合征——在老年男性中存在，并且与肌肉力量和骨密度下降以及记忆问题有关。本文回顾了低睾酮综合征（常被称为男性更年期或雄激素减退）存在的证据，以及新出现的证据，即睾酮治疗可能改善50岁以上男性的一些虚弱症状和体征。
