Petrikovsky B, Schneider E P, Klein V R, Wyse L J
Division of Maternal Fetal Medicine-North Shore University Hospital NYU School of Medicine, Manhasset, USA.
Fetal Diagn Ther. 1997 Jul-Aug;12(4):252-4. doi: 10.1159/000264479.
Two hundred and sixteen diagnostic cordocenteses were performed using the following technique: A guide was used to deliver the distal end of the needle to the immediate vicinity of the umbilical cord, after which the needle was released from the guide and a free-hand technique was used to enter the umbilical cord. The vessel punctured was identified by its sonographic appearance and flow direction using color Doppler technology. All procedure-related losses which occurred within 2 weeks were analyzed. The gestational age at the time of cordocentesis ranged from 18 to 42 weeks. Most punctures (62%) were performed at the placental insertion of the umbilical cord. In 32% of fetuses the free-floating loop was sampled and in 6% the puncture was performed at the site of cord entry into the fetus. Two fetuses died shortly after cordocentesis. One death occurred at 28 weeks in a fetus with severe cytomegalovirus infection. The other death was due to premature rupture of the membranes after the procedure in a very premature fetus. The overall fetal loss rate was 0.93%. In conclusion, the combination of the two cordocentesis techniques appears safe and highly successful in obtaining fetal blood samples.
采用以下技术进行了216例诊断性脐血穿刺：使用一根引导针将针的远端送至脐带附近，之后将针从引导针中释放，采用徒手技术刺入脐带。利用彩色多普勒技术通过超声图像和血流方向来识别被穿刺的血管。分析了所有在2周内发生的与操作相关的损失。脐血穿刺时的孕周为18至42周。大多数穿刺（62%）在脐带的胎盘附着处进行。32%的胎儿采集的是游离环，6%的穿刺在脐带进入胎儿的部位进行。两名胎儿在脐血穿刺后不久死亡。一例死亡发生在一名患有严重巨细胞病毒感染的28周胎儿。另一例死亡是由于在极早产胎儿的操作后胎膜早破。总体胎儿损失率为0.93%。总之，两种脐血穿刺技术相结合在获取胎儿血样方面似乎是安全且非常成功的。
