Honoré L H
Prostaglandins. 1976 Jun;11(6):1019-32. doi: 10.1016/0090-6980(76)90009-5.
A systematic gross and light microscopic study was done of 60 placentas, spontaneously delivered following induction by intra-amniotic PGF2alpha administration. The main findings were: high incidence of marginal and basal decidual hemorrhage, widespread degenerative changes in the decidua and chorionic villi, intervillous congestion and thrombosis and significant underfilling of the fetal vasculature. These changes are discussed in terms of the possible factors underlying the mechanism of prostaglandin-induced abortion.
对60例经羊膜腔内注射前列腺素F2α引产自然分娩的胎盘进行了系统的大体和光学显微镜研究。主要发现如下：边缘和基底蜕膜出血发生率高、蜕膜和绒毛膜广泛退行性变、绒毛间隙充血和血栓形成以及胎儿血管显著充盈不足。根据前列腺素诱导流产机制的潜在因素对这些变化进行了讨论。
