van 't Spijker A, ten Kroode H F
Department of Medical Psychology and Psychotherapy, Erasmus University Rotterdam, The Netherlands.
Patient Educ Couns. 1997 Sep-Oct;32(1-2):33-40. doi: 10.1016/s0738-3991(97)00066-9.
Presymptomatic DNA-testing for adult-onset diseases has serious psychological consequences. Here the psychological consequences of presymptomatic DNA-testing for Huntington's disease are reviewed. Both carriers and non-carriers experience emotional reactions after disclosure of their test result. However, up to today no long-term adverse emotional consequences have been revealed. Future research on other adult-onset genetic diseases should provide information about the reactions of children. In genetic counselling, attention should be paid to the reactions of people with a decreased risk. Genetic counselling must focus on the whole family and not on the individual applicant.
对成年发病疾病进行症状前DNA检测会产生严重的心理后果。本文综述了对亨廷顿舞蹈症进行症状前DNA检测的心理后果。携带者和非携带者在得知检测结果后都会产生情绪反应。然而，迄今为止尚未发现长期的不良情绪后果。未来针对其他成年发病的遗传疾病的研究应提供有关儿童反应的信息。在遗传咨询中，应关注风险降低人群的反应。遗传咨询必须关注整个家庭，而不是个体申请者。
