Shah D C, Haïssaguerre M, Jaïs P, Fischer B, Takahashi A, Hocini M, Clementy J
Service de Rhythmologie, Hôpital Cardiologique du Haut-Lévêque, Bordeaux-Pessac, France.
Circulation. 1997 Oct 21;96(8):2505-8. doi: 10.1161/01.cir.96.8.2505.
Despite verification of bidirectional conduction block after radiofrequency (RF) catheter ablation in the inferior vena cava (IVC)-tricuspid annulus (TA) isthmus, recurrence of common atrial flutter is relatively common. Although complete linear reablation is usually performed, we evaluated a simplified electrophysiological strategy selectively targeting recovered conducting isthmus tissue.
Twenty-one patients (18 men and 3 women, age, 54+/-10 years) with a recurrence of typical atrial flutter 6+/-7 months after an apparently successful catheter ablation in the IVC-TA isthmus prospectively underwent electrophysiologically targeted reablation during flutter. Sites with narrow electrograms or fractionated electrograms interposed between adjacent sites with double potentials considered to represent gaps were ablated without movement of the catheter. Mapping showed that 18 of 21 patients had a single gap. Successful ablation required a single application in 14 patients and, in the group as a whole, a median of one application (mean, 2+/-2; range, 1 to 11) with resultant bidirectional block in 13 of 16. A single narrow electrogram (duration, 48+/-6 ms; amplitude, 0.1+/-0.05 mV) was noted at the successful site in 11, whereas a fractionated electrogram (97+/-32 ms, 0.05+/-0.04 mV, P<.05) was noted in 9. There were four additional recurrences during a follow-up at 7+/-5 months; three were similarly ablated with a median of one pulse.
Transmural ablation lesions in the isthmus can be recognized during flutter by double potentials separated by an isoelectric interval. Postablation recurrent flutter is usually due to a single discrete recovered gap; this is represented by a single or a fractionated potential spanning the isoelectric interval of adjacent double potentials, which can be selectively targeted to minimize repeat ablation.
尽管在射频(RF)导管消融下腔静脉(IVC)-三尖瓣环(TA)峡部后已证实存在双向传导阻滞,但常见心房扑动的复发仍较为常见。虽然通常会进行完全线性再次消融,但我们评估了一种选择性针对恢复传导的峡部组织的简化电生理策略。
21例患者(18例男性和3例女性,年龄54±10岁),在IVC-TA峡部明显成功的导管消融术后6±7个月出现典型心房扑动复发,前瞻性地在心房扑动期间接受了电生理靶向再次消融。在不移动导管的情况下,对电图狭窄或在相邻双电位之间插入的碎裂电图部位(认为代表间隙)进行消融。标测显示21例患者中有18例存在单个间隙。14例患者单次消融成功,在整个组中,中位数为一次消融(平均2±2次;范围1至11次),16例中有13例产生双向阻滞。11例在成功部位记录到单个狭窄电图(持续时间48±6毫秒;振幅0.1±0.05毫伏),而9例记录到碎裂电图(97±32毫秒,0.05±0.04毫伏,P<0.05)。在7±5个月的随访期间又有4例复发;其中3例同样经中位数为一次脉冲的消融处理。
在心房扑动期间,峡部的透壁消融灶可通过等电位间期分隔的双电位识别。消融后复发的心房扑动通常归因于单个离散的恢复间隙;这由跨越相邻双电位等电位间期的单个或碎裂电位表示,可对其进行选择性靶向以尽量减少重复消融。