Worthy S A, Müller N L, Hartman T E, Swensen S J, Padley S P, Hansell D M
Department of Radiology, Vancouver Hospital and Health Sciences Centre, British Columbia, Canada.
Radiology. 1997 Nov;205(2):465-70. doi: 10.1148/radiology.205.2.9356630.
To determine whether infiltrative lung, airway, or vascular disease can be differentiated as the cause of mosaic attenuation on thin-section computed tomographic (CT) scans of the lung.
Thin-section CT scans were reviewed in 70 patients examined at three institutions. A mosaic attenuation pattern and pathologic or clinical proof of a specific type of disease were demonstrated. Causes of the mosaic pattern included infiltrative lung disease (n = 37), airway disease (n = 22), and vascular disease (n = 11). Thin-section CT findings were assessed independently by two observers blinded to clinical findings.
The type of disease was identified correctly at CT in 58 (83%) of 70 patients by observer 1 and 57 (81%) of 70 patients by observer 2. Infiltrative lung disease was diagnosed correctly by both observers in 34 (92%) of 37 cases. Observer 1 identified 21 (95%) of 22 cases of airway disease and three (27%) of 11 cases of vascular disease. Observer 2 identified 19 (86%) of 22 cases of airway disease and four (36%) of 11 cases of vascular disease.
Infiltrative lung disease and airway disease may be differentiated reliably as the cause of mosaic attenuation on lung CT scans, whereas vascular disease is often misinterpreted as infiltrative lung disease or airway disease.
确定在肺部薄层计算机断层扫描（CT）中，浸润性肺疾病、气道疾病或血管疾病能否作为导致马赛克样衰减的原因被区分开来。
回顾了在三个机构接受检查的70例患者的薄层CT扫描结果。显示出马赛克样衰减模式以及特定类型疾病的病理或临床证据。马赛克样模式的病因包括浸润性肺疾病（n = 37）、气道疾病（n = 22）和血管疾病（n = 11）。两位对临床结果不知情的观察者独立评估薄层CT表现。
观察者1在70例患者中的58例（83%）、观察者2在70例患者中的57例（81%）通过CT正确识别了疾病类型。两位观察者在37例浸润性肺疾病患者中的34例（92%）中正确诊断。观察者1识别出22例气道疾病中的21例（95%）和11例血管疾病中的3例（27%）。观察者2识别出22例气道疾病中的19例（86%）和11例血管疾病中的4例（36%）。
在肺部CT扫描中，浸润性肺疾病和气道疾病可作为导致马赛克样衰减的原因被可靠地区分，而血管疾病常被误诊为浸润性肺疾病或气道疾病。
