Brown T P, Garcia A, Kelley L
Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602, USA.
Avian Dis. 1997 Jul-Sep;41(3):604-9.
Spiking mortality of turkeys (SMT) is an infectious disease of 5-to-25-day-old turkey poults characterized by acute enteritis and bursal and thymic atrophy. Brooding 1-day-old poults on litter taken from naturally occurring cases successfully reproduced SMT 5 days postexposure. Oral exposure to an organ homogenate made of tissue samples from naturally occurring cases successfully reproduced SMT 5 days postinoculation. Coronaviruses were present in intestinal and bursal contents taken from poults with naturally occurring SMT. They were also present 5 days after exposure in the experimentally reproduced disease. Severe intestinal villus atrophy, bursal follicular lymphoid depletion, and thymic cortical atrophy were present histologically in naturally occurring SMT and in SMT reproduced by either experimental method.
火鸡猝死症（SMT）是一种发生于5至25日龄火鸡雏的传染病，其特征为急性肠炎以及法氏囊和胸腺萎缩。将1日龄雏火鸡饲养在取自自然发病病例的垫料上，暴露后5天成功再现了SMT。口服由自然发病病例的组织样本制成的器官匀浆，接种后5天成功再现了SMT。在患有自然发生的SMT的火鸡雏的肠道和法氏囊内容物中存在冠状病毒。在实验性再现疾病中，暴露后5天也存在冠状病毒。在自然发生的SMT以及通过任何一种实验方法再现的SMT中，组织学上均可见严重的肠绒毛萎缩、法氏囊滤泡性淋巴细胞耗竭和胸腺皮质萎缩。
