Randazzo G P, Wilson A R
Respiration. 1976;33(2):143-9. doi: 10.1159/000193727.
Changes of pulse rate and arterial blood gases were measured before, during, and after fiberoptic bronchoscopy in eleven patients with resting arterial PO2 breathing room air of 75 mm Hg or greater. Tachycardia was greatest after anesthesia (mean change greater than 20 beats/min) and declined thereafter. Hypoxemia was progressive from the time of entrance of the bronchoscope into the respiratory tree and continued into the immediate postbronchoscopic period when the mean fall was about 16 mm Hg. Mild hyperventilation was noted under all conditions. Since progressive hypoxemia persists following removal of the instrument and does not occur during rigid bronchoscopy, direct irritation causing reflex bronchospasm and the effects of aspirated secretions, anesthetic or lavage must be considered as possible causes for the hypoxemia.
对11名静息状态下呼吸室内空气时动脉血氧分压（PO2）为75mmHg或更高的患者，在纤维支气管镜检查前、检查期间和检查后测量了脉搏率和动脉血气。心动过速在麻醉后最为明显（平均变化大于20次/分钟），随后下降。从支气管镜进入呼吸道开始，低氧血症呈进行性发展，并持续到支气管镜检查后即刻，此时平均下降约16mmHg。在所有情况下均观察到轻度通气过度。由于在移除器械后仍持续存在进行性低氧血症，而在硬支气管镜检查期间未出现这种情况，因此必须考虑直接刺激导致反射性支气管痉挛以及吸出分泌物、麻醉剂或灌洗的影响是低氧血症的可能原因。
