Steinau G, Riesener K P, Schleef J, Steinau B, Schumpelick V
Department of Surgery, Medical Faculty, Rheinisch-Westphalian Technical University, Aachen, Germany.
Hepatogastroenterology. 1997 Sep-Oct;44(17):1513-8.
Thirty-one patients with Non-Hodgkin lymphoma of the stomach were retrospectively investigated. The prognostic factors regarding survival after treatment were determined in an univariate analysis. Twenty-seven of the patients revealed a stage I or II disease (according to the Ann Arbor classification) at the time of operation. The analysis showed no significance for grading, staging, lymph node-, serosa- or splenic involvement of our patients. Significant prognostic factors for survival of gastric Non-Hodgkin lymphomas were age (< 60 years) and resection margins R0 or R1/R2 (p < 0.05). The post-treatment evaluations for prognostic differentation between radical resections, patients with complete response after palliative resection including additional chemotherapy and patients without therapy response showed a significant difference in survival (p < 0.01).
对31例胃非霍奇金淋巴瘤患者进行了回顾性研究。通过单因素分析确定了治疗后生存的预后因素。27例患者在手术时显示为Ⅰ期或Ⅱ期疾病（根据Ann Arbor分类）。分析表明，患者的分级、分期、淋巴结、浆膜或脾脏受累情况无统计学意义。胃非霍奇金淋巴瘤生存的显著预后因素为年龄（<60岁）和切除切缘R0或R1/R2（p<0.05）。根治性切除、姑息性切除加化疗后完全缓解的患者和无治疗反应的患者之间的预后差异的治疗后评估显示，生存率有显著差异（p<0.01）。
