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外科医生视角下原发性胃淋巴瘤的管理

Management of primary gastric lymphomas from a surgeon's viewpoint.

作者信息

Ishizuka H, Kubota T, Hayashi N, Otani Y, Kumai K, Kitajima M

机构信息

Department of Surgery, Keio University School of Medicine, Keio University Hospital, Shinjuku-ku, Tokyo 160, Japan.

出版信息

Oncol Rep. 1999 Jan-Feb;6(1):103-6.

PMID:9864410
Abstract

Primary gastric lymphoma is a relatively uncommon disease and controversy still exists over its management. In order to assess prognostic factors of lymphomas, we carried out a retrospective study of 28 surgically treated gastric lymphoma patients. The overall survival rate for all the patients in the study was 33% at 10 years. On univariate analysis, lymph node metastasis and depth of tumor infiltration proved to be a significant prognostic factor while size and location of tumor, sex, and method of resection was not. From our results we believe that gastric lymphoma can be regarded as a localized disease in the early stages and a curative resection can be attained when aggressive surgery is possible.

摘要

原发性胃淋巴瘤是一种相对罕见的疾病,其治疗仍存在争议。为了评估淋巴瘤的预后因素,我们对28例接受手术治疗的胃淋巴瘤患者进行了一项回顾性研究。该研究中所有患者的10年总生存率为33%。单因素分析显示,淋巴结转移和肿瘤浸润深度是显著的预后因素,而肿瘤大小、位置、性别和切除方法则不是。根据我们的研究结果,我们认为胃淋巴瘤在早期可被视为局限性疾病,在可行积极手术时可实现根治性切除。

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