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事故发生6至10年后,切尔诺贝利清理人员淋巴细胞中的染色体畸变水平升高。

Increased level of chromosomal aberrations in lymphocytes of Chernobyl liquidators 6-10 years after the accident.

作者信息

Slozina N, Neronova E, Kharchenko T, Nikiforov A

机构信息

All-Russian Center of Ecological Medicine, Department of Clinical Cytogenetics, St. Petersburg, Russia.

出版信息

Mutat Res. 1997 Oct 6;379(2):121-5. doi: 10.1016/s0027-5107(97)00113-9.

Abstract

Chromosomal aberrations (CA) were used to investigate the level of cytogenetical damage in peripheral blood lymphocytes from the liquidators in a remote period (6-10 years) after the Chernobyl accident. There was a significantly higher frequency of chromosomal radiation markers (dicentrics and rings) in the peripheral lymphocytes of the liquidators than in the control subjects. No differences between these groups were demonstrated by the micronucleus (MN) test. Increased frequency of chromatid exchanges was associated with the smoking habits of the liquidators.

摘要

染色体畸变(CA)被用于研究切尔诺贝利事故发生后很长一段时间(6 - 10年)清理者外周血淋巴细胞中的细胞遗传学损伤水平。清理者外周淋巴细胞中染色体辐射标记物(双着丝粒和环状染色体)的频率显著高于对照组。微核(MN)试验未显示出这些组之间存在差异。染色单体交换频率的增加与清理者的吸烟习惯有关。

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