Rothwell D J, Hause L L, Koethe S, Straumfjord J V
Scand J Haematol. 1976 Apr;16(4):241-4. doi: 10.1111/j.1600-0609.1976.tb01144.x.
The electrophoretic mobility of erythrocytes from 3 patients with PNH was measured by standard techniques. Erythrocyte mobility is a measure of the net negative surface charge of these cells. In each of the 3 patients studied in mobility was significantly increased over normal cells indicating that there is an increase in negative surface charge of PNH erythrocytes. Following the Ham's and sucrose lysis tests; surviving cells showed mean mobilities that were not statistically different from normal cells. This suggests that these cells with higher surface charge are vulnerable to complement lysis.
采用标准技术测量了3例阵发性睡眠性血红蛋白尿（PNH）患者红细胞的电泳迁移率。红细胞迁移率是这些细胞净负表面电荷的一种度量。在所研究的3例患者中，每例患者的红细胞迁移率均显著高于正常细胞，这表明PNH红细胞的负表面电荷增加。在进行Ham试验和蔗糖溶血试验后，存活细胞的平均迁移率与正常细胞相比无统计学差异。这表明这些表面电荷较高的细胞易受补体溶解作用的影响。
