Vinogradova T, Volik S, Lebedev Y u, Shevchenko Y u, Lavrentyeva I, Khil P, Grzeschik K H, Ashworth L K, Sverdlov E
Shemyakin Institute of Bioorganic Chemistry, Russian Academy of Science, Miklukho-Maklaya, Moscow.
Gene. 1997 Oct 15;199(1-2):255-64. doi: 10.1016/s0378-1119(97)00376-4.
Seventy-two near full size long terminal repeats (LTRs) of human endogenous retrovirus of K-family (HERV-K) have been precisely located on the metric map of human chromosome 19. The LTR-related sequences were identified and assigned to cosmids by hybridization with two independent chromosome 19 specific cDNA clones corresponding to different parts of U3 region of LTR of HERV-K. The presence of full-size LTR sequences in a cosmid was further verified by PCR assay with a pair of primers complementary to the termini of the LTR. Coincidences of the LTR and the known genes positions are discussed.
