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水胶体敷料引起的变应性接触性皮炎。

Allergic contact dermatitis from hydrocolloid dressings.

作者信息

Sasseville D, Tennstedt D, Lachapelle J M

机构信息

Division of Dermatology, Royal Victoria Hospital, Montreal, QC, Canada.

出版信息

Am J Contact Dermat. 1997 Dec;8(4):236-8.

PMID:9358118
Abstract

BACKGROUND

Hydrocolloid wound dressings have been in use for nearly two decades, and have rarely caused allergic contact dermatitis. DuoDERM E (DuoDERM CGF) is a newer version of DuoDERM (ConvaTec Ltd, a division of Bristol-Myers Squibb Co, Princeton, NJ) that contains a sensitizing derivative of colophony.

OBJECTIVE

We describe three patients who developed eczematous lesions under this type of wound covering.

METHODS

The patients were patch tested to the European standard series, to a glues and adhesives series, and to pieces of various adhesive dressings.

RESULTS

The patients displayed positive patch tests to colophony and to DuoDERM E or DuoDERM CGF hydrocolloid dressings.

CONCLUSION

These dressings contain the pentaerythritol ester of hydrogenated rosin as a tackifying agent, and this substance retains the sensitizing potential of colophony. The addition of this compound is an important change that may negatively alter the good safety record of ConvaTec dressings.

摘要

背景

水胶体伤口敷料已使用近二十年,很少引起过敏性接触性皮炎。多德美E(多德美CGF)是多德美(康维德有限公司,百时美施贵宝公司的一个部门,新泽西州普林斯顿)的新版本,含有一种致敏性的松香衍生物。

目的

我们描述了三名在这种伤口覆盖物下出现湿疹样皮损的患者。

方法

对患者进行欧洲标准系列、胶水和粘合剂系列以及各种粘性敷料片的斑贴试验。

结果

患者对松香以及多德美E或多德美CGF水胶体敷料的斑贴试验呈阳性。

结论

这些敷料含有氢化松香季戊四醇酯作为增粘剂,该物质保留了松香的致敏潜力。这种化合物的添加是一个重要变化,可能会对康维德敷料良好的安全记录产生负面影响。

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