Suzuki K, Kurokawa K, Suzuki T, Yoshida I, Otaki A, Imai K, Yamanaka H
Department of Urology, Gunma University School of Medicine, Maebashi, Japan.
Eur Urol. 1997;32(3):371-4.
To assess the anterior mediastinal mass in recurrent testicular cancer, with relation to thymic hyperplasia after treatment.
The anterior mediastinal regions were fully evaluated by chest computed tomography (CT) at the initial staging and after treatment in 24 of 44 patients with testicular cancer.
One patient with stage IIB tumor had thymic hyperplasia before treatment, and one with stage III had benign thymic hyperplasia after chemotherapy with salvage surgery. Three of 4 patients who had recurrence had an anterior mediastinal mass. One had benign thymic hyperplasia confirmed by histology and 2 had metastatic tumor confirmed by histology and clinical course, in which the mass became so enlarged that it obstructed major vessels.
Although the relationship of the CT finding to the response to treatment in the anterior mediastinal mass and other metastatic lesions provide some clues helpful in differentiating benign from malignant masses, surgical exploration is recommended for the patient with an indication for salvage surgery.
评估复发性睾丸癌患者的前纵隔肿块，并探讨其与治疗后胸腺增生的关系。
对44例睾丸癌患者中的24例，在初始分期及治疗后通过胸部计算机断层扫描（CT）对前纵隔区域进行全面评估。
1例IIB期肿瘤患者在治疗前有胸腺增生，1例III期患者在挽救性手术后化疗后出现良性胸腺增生。4例复发患者中有3例有前纵隔肿块。1例经组织学证实为良性胸腺增生，2例经组织学和临床病程证实为转移性肿瘤，肿块增大至阻塞大血管。
尽管前纵隔肿块及其他转移灶的CT表现与治疗反应的关系为鉴别良性与恶性肿块提供了一些有用线索，但对于有挽救性手术指征的患者，建议进行手术探查。
