Kathuria P, Moore H L, Khanna R, Twardowski Z J, Goel S, Nolph K D
Department of Internal Medicine, University of Missouri, Columbia 65212, USA.
Perit Dial Int. 1997 Sep-Oct;17(5):449-54.
To determine if peritoneal dialysis modality has an impact on protein losses in dialysate.
Retrospective, cross-sectional study.
190 patients who had selected peritoneal dialysis were classified into one of four transport categories (high, high-average, low-average, or low) based on standard peritoneal equilibration test results. Patients were then assigned to continuous ambulatory peritoneal dialysis (CAPD) or nightly intermittent peritoneal dialysis (NIPD) based on membrane transport characteristics and individual preferences.
Patients with similar membrane transport characteristics had essentially no differences in dialysate protein and albumin losses whether treated with CAPD or NIPD.
Although high transporters may be better managed with short-dwell therapies such as nocturnal intermittent peritoneal dialysis or daily ambulatory peritoneal dialysis, consistent marked decreases in protein losses cannot be cited as a benefit of NIPD over CAPD.
确定腹膜透析方式是否对透析液中的蛋白质丢失有影响。
回顾性横断面研究。
190例选择腹膜透析的患者根据标准腹膜平衡试验结果被分为四种转运类别（高、高平均、低平均或低）之一。然后根据膜转运特性和个人偏好将患者分配至持续非卧床腹膜透析（CAPD）或夜间间歇性腹膜透析（NIPD）。
具有相似膜转运特性的患者，无论接受CAPD还是NIPD治疗，其透析液蛋白质和白蛋白丢失基本无差异。
尽管高转运者采用夜间间歇性腹膜透析或每日非卧床腹膜透析等短驻留疗法可能管理得更好，但不能将蛋白质丢失持续显著减少作为NIPD优于CAPD的一个益处。
