Gaither C A, Bagozzi R P, Ascione F J, Kirking D M
College of Pharmacy, University of Michigan, Ann Arbor, USA.
Pharm Res. 1997 Oct;14(10):1298-308. doi: 10.1023/a:1012143915886.
To improve upon the theory of reasoned action and apply it to pharmaceutical research, we investigated the effects of relevant appraisals attributes, and past behavior of physicians on the use of drug information sources. We also examined the moderating effects of practice characteristics.
A mail questionnaire asked HMO physicians to evaluate seven common sources of drug information on general appraisals (degree of usefulness and ease of use), specific attributes (availability, quality of information on harmful effects and on drug efficacy), and past behavior when searching for information on a new, simulated H2 antagonist agent. Semantic differential scales were used to measure each appraisal, attribute and past behavior. Information was also collected on practice characteristics.
Findings from 108/200 respondents indicated that appraisals and attributes were useful determinants of attitudes and subjective norms toward use. Degree of usefulness and quality of information on harmful effects were important predictors of attitudes toward use for several sources of information. Ease of use and degree of usefulness were important predictors of subjective norms toward use. In many cases, moderating effects of practice characteristics were in opposing directions. Past behavior had significant direct effects on attitudes toward the PDR.
The findings suggest ways to improve the usefulness of the theory of reasoned action as a model of decision-making. We also propose practical guidelines that can be used to improve the types of drug information sources used by physicians.
为完善理性行动理论并将其应用于药物研究，我们调查了相关评估属性以及医生过去行为对药物信息来源使用的影响。我们还研究了实践特征的调节作用。
通过邮寄问卷，要求健康维护组织（HMO）的医生对七种常见的药物信息来源在总体评估（有用程度和易用程度）、具体属性（可获取性、关于有害作用和药物疗效的信息质量）以及在查找一种新的模拟H2拮抗剂信息时的过去行为方面进行评估。使用语义差异量表来测量每种评估、属性和过去行为。还收集了关于实践特征的信息。
200名受访者中有108人的调查结果表明，评估和属性是使用态度和主观规范的有用决定因素。有用程度和关于有害作用的信息质量是几种信息来源使用态度的重要预测因素。易用程度和有用程度是使用主观规范的重要预测因素。在许多情况下，实践特征的调节作用方向相反。过去行为对《医师案头参考手册》（PDR）的态度有显著直接影响。
研究结果提出了完善理性行动理论作为决策模型有用性的方法。我们还提出了实用指南，可用于改善医生使用的药物信息来源类型。
