Ziegler M G, Lew P, Singer B C
Department of Medicine, University of California at San Diego School of Medicine, USA.
JAMA. 1995 Apr 26;273(16):1296-8.
To provide quantitative data about the accuracy of the information about drugs presented to physicians by pharmaceutical sales representatives.
One hundred six statements about drugs made during 13 presentations by pharmaceutical representatives were analyzed for accuracy. Statements were rated inaccurate if they contradicted the 1993 Physicians' Desk Reference or material quoted or handed out by the sales representative.
University teaching hospital.
Twelve (11%) of 106 statements about drugs were inaccurate. All 12 inaccurate statements were favorable toward the promoted drug, whereas 39 (49%) of 79 accurate statements were favorable (P = .005). None of 15 statements about competitors' drugs were favorable, but all were accurate, significantly P < .001) differing from statements about promoted drugs. In a survey of 27 physicians who attended these presentations, seven (26%) recalled any false statement made by a pharmaceutical representative, and 10 (37%) said information from the representatives influenced the way they prescribed drugs.
Eleven percent of the statements made by pharmaceutical representatives about drugs contradicted information readily available to them. Physicians generally failed to recognize the inaccurate statements.
提供有关药品销售代表向医生提供的药品信息准确性的定量数据。
分析了药品代表在13次介绍过程中做出的106条关于药品的陈述的准确性。如果陈述与《1993年医师案头参考手册》或销售代表引用或分发的材料相矛盾，则被评为不准确。
大学教学医院。
106条关于药品的陈述中有12条（11%）不准确。所有12条不准确的陈述都对促销药品有利，而79条准确陈述中有39条（49%）是有利的（P = 0.005）。关于竞争对手药品的15条陈述中没有一条是有利的，但都是准确的，与关于促销药品的陈述有显著差异（P < 0.001）。在对参加这些介绍会的27名医生进行的调查中，7名（26%）回忆起药品代表做出的任何虚假陈述，10名（37%）表示代表提供的信息影响了他们开药的方式。
药品代表做出的关于药品的陈述中有11%与他们 readily available to them的信息相矛盾。医生通常未能识别出不准确的陈述。
