Obendorf D L, Statham P, Driessen M
Mt. Pleasant Laboratories, Tasmania, Australia.
J Wildl Dis. 1996 Oct;32(4):623-6. doi: 10.7589/0090-3558-32.4.623.
Sera from 150 eastern barred bandicoots (Perameles gunnii) were collected from two study sites in southern Tasmania between 1992 and 1995. Samples were tested for antibodies to the protozoan parasite, Toxoplasma gondii, using formalin-treated tachyzoites as the antigen in direct (DAT) and modified agglutination tests (MAT). Cut-off titers were set based on confirmed cases of toxoplasmosis in this species. A total of 133 animals (89%) were classified as negative, seven (4.6%) had suspicious reactions, and 10 (6.7%) were diagnosed as positive. Five of the 10 positive animals were not retrapped after initial seroconversion; another three animals recorded high MAT titers on two consecutive bleedings, three months apart. Of the remaining two sero-positive bandicoots, one was found dead in a trap and generalized toxoplasmosis was diagnosed at necropsy, while the other animal had central nervous system disabilities consistent with toxoplasmosis but was accidently released and never recaptured. Based on these findings we propose that eastern barred bandicoots are likely to be highly susceptible to primary T. gondii infection.
1992年至1995年间，从塔斯马尼亚岛南部的两个研究地点采集了150只东部袋狸（Perameles gunnii）的血清。以经福尔马林处理的速殖子为抗原，采用直接凝集试验（DAT）和改良凝集试验（MAT）检测样本中针对原生动物寄生虫刚地弓形虫的抗体。根据该物种确诊的弓形虫病病例设定临界滴度。共有133只动物（89%）被归类为阴性，7只（4.6%）有可疑反应，10只（6.7%）被诊断为阳性。10只阳性动物中有5只在初次血清转化后未被重新捕获；另外3只动物在相隔三个月的两次连续采血中MAT滴度较高。在其余两只血清阳性的袋狸中，一只在陷阱中死亡，尸检时诊断为全身性弓形虫病，而另一只动物有与弓形虫病相符的中枢神经系统残疾，但意外放生后未再捕获。基于这些发现，我们认为东部袋狸可能对刚地弓形虫的初次感染高度易感。
