Hamir A N, Klein L
School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348, USA.
J Wildl Dis. 1996 Oct;32(4):674-7. doi: 10.7589/0090-3558-32.4.674.
During March 1988, a case of bilateral polycystic kidney disease (PKD) occurred in an aged raccoon (Procyon lotor) at a zoo in Wilmington, Delaware (USA). Prior to its death, the raccoon had no clinical signs. On necropsy there was bilateral enlargement of kidneys which, on cut sections, had many variable sized fluid-filled cystic cavities. Endometrial hyperplasia with presence of multiple variable-sized cysts were also seen in the uterus of this raccoon. Microscopical examinations were characteristic of an end-stage renal failure due to PKD. Neither PKD nor cystic endometerial hyperplasia appears to have been previously described in this species.
1988年3月，美国特拉华州威尔明顿市一家动物园的一只老年浣熊（北美浣熊）出现双侧多囊肾病（PKD）病例。这只浣熊在死亡前没有任何临床症状。尸检发现双侧肾脏肿大，切开后可见许多大小不一的充满液体的囊腔。在这只浣熊的子宫内还发现了子宫内膜增生并伴有多个大小不一的囊肿。显微镜检查显示为多囊肾病导致的终末期肾衰竭特征。此前该物种似乎未曾有过关于多囊肾病或囊性子宫内膜增生的描述。
