Chang C C, Lee H F, Tsai H D, Lo H Y
Department of Obstetrics and Gynecology, China Medical College Hospital, Taiwan.
Int J Gynaecol Obstet. 1997 Oct;59(1):31-4. doi: 10.1016/s0020-7292(97)00122-7.
Recurrent endometriomas after medical or surgical treatment is a difficult clinical problem for those patients who wish to perform ovulation induction. Therefore we tried to investigate the efficacy of sclerotherapy as an adjuvant management before ovulation induction to preserve more ovarian tissue for folliculogenesis in ART program.
Thirty-two patients with persistent or recurrent endometrioma after surgical or medical treatment were included in this study. Transvaginal ultrasound needle guided aspiration of the cyst followed by tetracycline instillation was performed before ovulation induction.
There is an encouraging clinical pregnancy rate of 34.37%. Also, there is a disappointing recurrent rate of 46.87% in 12 months follow-up course.
The increased interest in cost-effective outpatient therapy and the expected difficulty in surgical treatment of recurrent endometriomas made aspiration and sclerotherapy of endometrioma an attractive option before ovulation induction.
对于那些希望进行排卵诱导的患者而言，药物或手术治疗后复发性卵巢子宫内膜异位囊肿是一个棘手的临床问题。因此，我们试图研究硬化疗法作为排卵诱导前辅助治疗的疗效，以便在辅助生殖技术（ART）程序中保留更多卵巢组织用于卵泡生成。
本研究纳入了32例经手术或药物治疗后仍存在持续性或复发性卵巢子宫内膜异位囊肿的患者。在排卵诱导前，通过经阴道超声引导下对囊肿进行穿刺抽吸，随后注入四环素。
临床妊娠率为34.37%，令人鼓舞。此外，在12个月的随访过程中，复发率为46.87%，令人失望。
对经济高效的门诊治疗的兴趣增加，以及复发性卵巢子宫内膜异位囊肿手术治疗预期的困难，使得对卵巢子宫内膜异位囊肿进行穿刺抽吸和硬化疗法成为排卵诱导前一个有吸引力的选择。
