Foley K O, Brubaker P H, Matrazzo B, Berry M J, Pribanich S, Miller H S
Department of Medicine, Wake Forest University, Winston-Salem, North Carolina 27109, USA.
Am J Cardiol. 1997 Nov 1;80(9):1215-6. doi: 10.1016/s0002-9149(97)00642-5.
The effects of cardioselective beta blockade on ventilation and gas exchange were investigated in 12 male subjects with coronary artery disease during ramp treadmill testing. Patients were able to maintain much of their functional capacity as measured by oxygen consumption in the beta-blocked condition, and also maintained minute ventilation by increasing respiratory rate despite a decrease in tidal volume.
在12名患有冠状动脉疾病的男性受试者进行斜坡跑步机测试期间,研究了心脏选择性β受体阻滞剂对通气和气体交换的影响。在使用β受体阻滞剂的情况下,患者能够维持大部分通过耗氧量测量的功能能力,并且尽管潮气量减少,但通过增加呼吸频率维持了每分通气量。