Hildenbrand G L, Hildenbrand L C, Bradford K, Cavin S W
Gerson Research Organization, San Diego, Calif., USA.
Altern Ther Health Med. 1995 Sep;1(4):29-37.
Compare 5-year melanoma survival rates to rates in medical literature.
Retrospective.
Hospital in Tijuana, Mexico.
White adult patients (N = 153) with superficial spreading and nodular melanoma, aged 25-72 years.
Gerson's diet therapy: lactovegetarian; low sodium, fat and (temporarily) protein; high potassium, fluid, and nutrients (hourly raw vegetable/fruit juices). Metabolism increased by thyroid; calorie supply limited to 2600-3200 calories per day. Coffee enemas as needed for pain and appetite.
5-year survival rates by stage at admission.
Of 14 patients with stages I and II (localized) melanoma, 100% survived for 5 years, compared with 79% of 15,798 reported by Balch. Of 17 with stage IIIA (regionally metastasized) melanoma, 82% were alive at 5 years, in contrast to 39% of 103 from Fachklinik Hornheide. Of 33 with combined stages IIIA + IIIB (regionally metastasized) melanoma, 70% lived 5 years, compared with 41% of 134 from Fachklinik Hornheide. We propose a new stage division: IVA (distant lymph, skin, and subcutaneous tissue metastases), and IVB (visceral metastases). Of 18 with stage IVA melanoma, 39% were alive at 5 years, compared with only 6% of 194 from the Eastern Cooperative Oncology Group. Survival impact was not assessed for stage IVB. Male and female survival rates were identical for stages I-IIIB, but stage IVA women had a strong survival advantage.
The 5-year survival rates reported here are considerably higher than those reported elsewhere. Stage IIIA/B males had exceptionally high survival rates compared with those reported by other centers.
将黑色素瘤5年生存率与医学文献中的生存率进行比较。
回顾性研究。
墨西哥蒂华纳的一家医院。
年龄在25至72岁之间、患有浅表扩散性和结节性黑色素瘤的白人成年患者（N = 153）。
格森饮食疗法：乳类素食；低钠、低脂肪且（暂时）低蛋白；高钾、高液体量及高营养（每小时饮用生蔬菜/水果汁）。通过甲状腺提高新陈代谢；每日热量供应限制在2600 - 3200卡路里。根据疼痛和食欲需要进行咖啡灌肠。
入院时各阶段的5年生存率。
14例I期和II期（局限性）黑色素瘤患者中，100%存活5年，相比之下，巴尔奇报告的15798例患者中这一比例为79%。17例IIIA期（区域转移）黑色素瘤患者中，82%在5年后仍存活，而霍恩海德专科诊所报告的103例患者中这一比例为39%。33例IIIA + IIIB期（区域转移）黑色素瘤患者中，70%存活5年，相比之下，霍恩海德专科诊所报告的134例患者中这一比例为41%。我们提出一个新的分期：IVA期（远处淋巴结、皮肤及皮下组织转移）和IVB期（内脏转移）。18例IVA期黑色素瘤患者中，39%在5年后仍存活，相比之下，东部肿瘤协作组报告的194例患者中这一比例仅为6%。未对IVB期的生存影响进行评估。I - IIIB期男性和女性的生存率相同，但IVA期女性具有显著的生存优势。
此处报告的5年生存率远高于其他地方报告的生存率。与其他中心报告的情况相比，IIIA/B期男性的生存率异常高。
