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Nimbus/匹兹堡大学(UOP)轴流左心室辅助系统的持续研发。

Continued development of the Nimbus/University of Pittsburgh (UOP) axial flow left ventricular assist system.

作者信息

Thomas D C, Butler K C, Taylor L P, Le Blanc P, Griffith B P, Kormos R L, Borovetz H S, Litwak P, Kameneva M V, Choi S, Burgreen G W, Wagner W R, Wu Z, Antaki J F

机构信息

Nimbus Inc., Rancho Cordova, California 95670, USA.

出版信息

ASAIO J. 1997 Sep-Oct;43(5):M564-6.

PMID:9360107
Abstract

Nimbus and the University of Pittsburgh (UOP) have continued the development of a totally implanted axial flow blood pump under the National Institutes of Health (NIH) Innovative Ventricular Assist System (IVAS) program. This 62 cc device has an overall length of 84 mm and an outer diameter of 34.5 mm. The inner diameter of the blood pump is 12 mm. It is being designed to be a totally implanted permanent device. A key achievement during the past year was the completion of the Model 2 pump design. Ten of these pumps have been fabricated and are being used to conduct in vitro and in vivo experiments to evaluate the performance of different materials and hydraulic components. Efforts for optimizing the closed loop speed control have continued using mathematical modeling, computer simulations, and in vitro and in vivo testing. New hydraulic blade designs have been tested using computational fluid dynamics (CFD) and flow visualization. A second generation motor was designed with improved efficiency. To support the new motor, a new motor controller fabricated as a surface mount PC board has been completed. The program is now operating under a formal QA system.

摘要

宁布斯公司与匹兹堡大学(UOP)在美国国立卫生研究院(NIH)的创新心室辅助系统(IVAS)项目下,继续推进一款完全植入式轴流血泵的研发。这款62立方厘米的设备总长84毫米,外径34.5毫米。血泵的内径为12毫米。它被设计成一款完全植入式的永久性设备。过去一年的一项关键成果是完成了2型泵的设计。已制造出10台这样的泵,并用于进行体外和体内实验,以评估不同材料和液压部件的性能。利用数学建模、计算机模拟以及体外和体内测试,继续致力于优化闭环速度控制。已使用计算流体动力学(CFD)和流动可视化技术对新的液压叶片设计进行了测试。设计了第二代电机,其效率有所提高。为支持新电机,已完成一款作为表面贴装印刷电路板制造的新型电机控制器。该项目目前在一个正式的质量保证系统下运行。

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