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女童腹股沟疝合并男性假两性畸形的发病率。

The incidence of male hermaphroditism in girls with inguinal hernia.

作者信息

Nielsen D F, Bülow S

出版信息

Surg Gynecol Obstet. 1976 Jun;142(6):875-6.

PMID:936033
Abstract

The incidence of male hermaphroditism in girls with inguinal hernias is estimated to be 1.4 per cent. From 1961 to 1972, 340 girls were admitted to the Department of Surgery at St. Josephs Hospital for hernial repair. One hundred and two patients had menstruated prior to the follow-up study. Buccal smears from the remaining patients were examined for Y chromatin-positive cells. We observed a zero per cent rate of male hermaphroditism, which is not significantly different from the aforementioned frequency, p greater than 0.05. Large scale prospective studies must be available before any conclusion can be drawn as to whether or not determination of the genetic gender prior to hernial repair in girls should be conducted as a routine procedure.

摘要

女童腹股沟疝合并男性假两性畸形的发生率估计为1.4%。1961年至1972年期间,340名女童因疝修补术入住圣约瑟夫医院外科。在随访研究之前,102名患者已经月经初潮。对其余患者的口腔涂片进行Y染色质阳性细胞检查。我们观察到男性假两性畸形的发生率为零,与上述发生率无显著差异,p大于0.05。在就女童疝修补术前是否应常规进行遗传性别判定得出任何结论之前,必须开展大规模前瞻性研究。

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