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从中国香港和美国密西西比州的鸭子中分离出的禽副粘病毒之间的抗原和结构关系

Antigenic and structural relationships between avian paramyxoviruses isolated from ducks in Hong Kong and Mississippi, U.S.A.

作者信息

Alexander D J, Aymard M, Kessler N, Collins M S

出版信息

J Gen Virol. 1979 Sep;44(3):839-42. doi: 10.1099/0022-1317-44-3-839.

Abstract

Representative isolates of the paramyxoviruses duck/Hong Kong/75 and duck/Mississippi/75 were shown to be serologically closely related by haemagglutination and neuraminidase inhibition tests. The structural polypeptides of these viruses were also shown to be similar. For each of the isolates tested, polyacrylamide gel electrophoresis in the presence of SDS revealed a similar polypeptide pattern consisting, under reducing conditions, of seven polypeptides with apparent mol. wt. ranging from 46000 to 190000. Each virus had two glycosylated polypeptides with apparent mol. wt. of 56000 and 71000 to 72000 under reducing conditions and 62000 to 63000 and 135000 to 142000 under non-reducing conditions.

摘要

通过血凝试验和神经氨酸酶抑制试验表明,副粘病毒鸭/香港/75和鸭/密西西比/75的代表性分离株在血清学上密切相关。这些病毒的结构多肽也显示出相似性。对于所测试的每种分离株,在SDS存在下进行的聚丙烯酰胺凝胶电泳显示出相似的多肽图谱,在还原条件下,由七条多肽组成,其表观分子量范围为46000至190000。每种病毒在还原条件下有两条糖基化多肽,表观分子量分别为56000和71000至72000,在非还原条件下为62000至63000和135000至142000。

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