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苏丹北部沙漠绵羊对曼氏血吸虫感染的易感性。

Susceptibility of desert sheep to infection with Schistosoma mansoni of Northern Sudan.

作者信息

Adam S E, Magzoub M

出版信息

Vet Pathol. 1976;13(3):211-5. doi: 10.1177/030098587601300305.

DOI:10.1177/030098587601300305
PMID:936426
Abstract

Each of two Desert Sheep was infected with 1500 cercariae of Schistosoma mansoni of Northern Sudan. Signs of infection were anorexia, soft faces, progressive weakness and loss of wool. The sheep were killed 254 and 269 days after infection. The findings were heavy infiltration of the lamina propria with inflammatory cells, numerous ova in the submucosa, hyperplasia of lymphoid tissue, oedema of the mesenteric lymph nodes, and focal pulmonary oedema and congestion. There were egg granulomas, focal necrosis, schistosomal pigment, fatty change, depletion of glycogen and reduction in the activity of adenosine triphosphatase, succinic tetrazolium reductase and glucose-6-phosphatase in the liver. In one sheep 1330 cercariae penetrated and 700 matured to produce males and females in a 5:2 ratio. In the other sheep, about one third of the cercariae penetrated and matured. The ratio of males to females was 3:1.

摘要

两只荒漠绵羊分别感染了1500条苏丹北部曼氏血吸虫尾蚴。感染症状包括厌食、脸部柔软、进行性虚弱和脱毛。绵羊在感染后254天和269天被宰杀。结果发现固有层有大量炎性细胞浸润,黏膜下层有大量虫卵,淋巴组织增生,肠系膜淋巴结水肿,以及局灶性肺水肿和充血。肝脏出现虫卵肉芽肿、局灶性坏死、血吸虫色素、脂肪变性、糖原消耗以及三磷酸腺苷酶、琥珀酸四氮唑还原酶和葡萄糖-6-磷酸酶活性降低。在一只绵羊中,1330条尾蚴侵入,700条发育成熟,雌雄比例为5:2。在另一只绵羊中,约三分之一的尾蚴侵入并发育成熟,雌雄比例为3:1。

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