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斯洛文尼亚一名拉龙综合征患者接受IGF-I五年治疗（随访报告）

Five year treatment with IGF-I of a patient with Laron syndrome in Slovenia (a follow-up report).

作者信息

Krzisnik C, Battelino T

机构信息

Department of Paediatrics, University Medical Centre Ljubljana, Slovenia.

出版信息

J Pediatr Endocrinol Metab. 1997 Jul-Aug;10(4):443-7. doi: 10.1515/jpem.1997.10.4.443.

DOI:10.1515/jpem.1997.10.4.443
PMID:9364374
Abstract

This is a follow-up report of a 14 1/2 year-old boy with Laron syndrome, who received twice daily therapy with IGF-I 120 micrograms/kg for 5 years that resulted in a linear growth of 40 cm. Concomitantly he became very obese which is attributed to IGF-I action via the insulin receptors.

摘要

这是一份关于一名14岁半患有拉伦综合征男孩的随访报告。该男孩接受了为期5年的每日两次、剂量为120微克/千克的胰岛素样生长因子-1（IGF-I）治疗，身高增长了40厘米。与此同时，他变得非常肥胖，这归因于IGF-I通过胰岛素受体发挥的作用。

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引用本文的文献

1
Insulin-like growth factor 1 (IGF-1): a growth hormone.胰岛素样生长因子1（IGF-1）：一种生长激素。
Mol Pathol. 2001 Oct;54(5):311-6. doi: 10.1136/mp.54.5.311.