Krzisnik C, Battelino T
Department of Paediatrics, University Medical Centre Ljubljana, Slovenia.
J Pediatr Endocrinol Metab. 1997 Jul-Aug;10(4):443-7. doi: 10.1515/jpem.1997.10.4.443.
This is a follow-up report of a 14 1/2 year-old boy with Laron syndrome, who received twice daily therapy with IGF-I 120 micrograms/kg for 5 years that resulted in a linear growth of 40 cm. Concomitantly he became very obese which is attributed to IGF-I action via the insulin receptors.
这是一份关于一名14岁半患有拉伦综合征男孩的随访报告。该男孩接受了为期5年的每日两次、剂量为120微克/千克的胰岛素样生长因子-1(IGF-I)治疗,身高增长了40厘米。与此同时,他变得非常肥胖,这归因于IGF-I通过胰岛素受体发挥的作用。