Gaĭdamovich S Ia, Kocherovskaia M Iu
Vopr Virusol. 1976 Mar-Apr(2):223-6.
Infection of mice with strain No. 325 of lymphocytic choriomeningitis virus (LCM) isolated in Moscow was of two types depending on the age of the animals at the time of inoculation. Infection in adult mice terminated either in death or recovery with development of immunity. Inoculation of suckling mice resulted in formation of chronic virus carrier state in most survivors. The indirect hemagglutination inhibition test was found to be very sensitive for detection of antibody in convalescent animals as well as in mice with chronic LCM infection.
用在莫斯科分离出的淋巴细胞性脉络丛脑膜炎病毒(LCM)325号菌株感染小鼠,根据接种时动物的年龄,感染分为两种类型。成年小鼠感染后要么死亡,要么康复并产生免疫力。给乳鼠接种后,大多数存活者会形成慢性病毒携带状态。间接血凝抑制试验被发现对检测恢复期动物以及慢性LCM感染小鼠体内的抗体非常敏感。