Johnson T M, Headington J T, Baker S R, Lowe L
University of Michigan Medical Center, Ann Arbor, USA.
J Am Acad Dermatol. 1997 Nov;37(5 Pt 1):758-64. doi: 10.1016/s0190-9622(97)70114-2.
Management of lentigo maligna (LM) and lentigo maligna melanoma (LMM) may present problems because of the characteristic, yet unpredictable, subclinical peripheral and periadnexal extension of atypical junctional melanocytic hyperplasia beyond the visible margins.
We used paraffin-embedded (permanent) peripheral vertical section margin control in a staged fashion in the management of LM and LMM.
We used a modification of surgical excision in a staged fashion by means of a two-bladed knife with permanent peripheral vertical section margin control.
This method is technically easy and results in complete histologic evaluation of the peripheral margins without compromising the measurement of tumor thickness of the primary melanoma.
The use of the "square" procedure, a staged excision with permanent peripheral vertical section margin control, is useful in the management of LM and LMM.
恶性雀斑样痣(LM)和恶性雀斑样痣黑色素瘤(LMM)的治疗可能会出现问题,因为非典型交界性黑素细胞增生具有特征性但不可预测的亚临床外周和腺周扩展,超出可见边缘。
我们在LM和LMM的治疗中采用分期的石蜡包埋(永久性)外周垂直切片边缘控制。
我们通过使用带有永久性外周垂直切片边缘控制的双刃刀,以分期方式对手术切除进行了改良。
该方法技术上简便,可对外周边缘进行完整的组织学评估,而不会影响原发性黑色素瘤肿瘤厚度的测量。
采用“方形”手术,即分期切除并进行永久性外周垂直切片边缘控制,对LM和LMM的治疗有用。