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先天性冠状动脉异常的流行病学:一项针对中欧人群的冠状动脉造影研究。

Epidemiology of congenital coronary artery anomalies: a coronary arteriography study on a central European population.

作者信息

Kardos A, Babai L, Rudas L, Gaál T, Horváth T, Tálosi L, Tóth K, Sárváry L, Szász K

机构信息

Second Department of Medicine, Albert Szent-Györgyi Medical University, Szeged, Hungary.

出版信息

Cathet Cardiovasc Diagn. 1997 Nov;42(3):270-5. doi: 10.1002/(sici)1097-0304(199711)42:3<270::aid-ccd8>3.0.co;2-9.

DOI:10.1002/(sici)1097-0304(199711)42:3<270::aid-ccd8>3.0.co;2-9
PMID:9367100
Abstract

The anatomical patterns and frequency of occurrence of congenital coronary anomalies (CCA) in a Central European cohort has not yet been studied. The angiographic data of 7,694 consecutive patients undergoing coronary arteriography at the Albert Szent-Györgyi Medical University, Szeged, Hungary, from 1984 to 1994 were analyzed. CCA were found in 103 patients (1.34% incidence). Ninety-eight of them (95.2%) had anomalies of origin and distribution, and five (4.8%) had coronary artery fistulae. The incidence was the highest for the separate origin of left descending artery and left circumflex from the left sinus of Valsalva (52.42%). Anomalous origin of the left circumflex coronary artery from the right coronary was 8.7% while from the right sinus of Valsalva 18.4%. CCA, which may be associated with potentially serious events, such as ectopic coronary origin from the opposite aortic sinus (1.9%) and single coronary arteries (3.88%), were not frequent. The incidence of CCA in the Central European cohort under study was similar to that of the largest North American study. The anatomic classification presented can be useful from both clinical and surgical standpoints.

摘要

中欧人群中先天性冠状动脉异常(CCA)的解剖模式和发生率尚未得到研究。对1984年至1994年在匈牙利塞格德的阿尔伯特· Szent-Györgyi医科大学连续接受冠状动脉造影的7694例患者的血管造影数据进行了分析。103例患者(发生率1.34%)发现有CCA。其中98例(95.2%)有起源和分布异常,5例(4.8%)有冠状动脉瘘。左前降支和左旋支分别起源于左冠状动脉窦的发生率最高(52.42%)。左旋支冠状动脉起源于右冠状动脉的发生率为8.7%,起源于右冠状动脉窦的发生率为18.4%。可能与潜在严重事件相关的CCA,如冠状动脉异位起源于对侧主动脉窦(1.9%)和单支冠状动脉(3.88%)并不常见。所研究的中欧人群中CCA的发生率与北美最大规模研究的发生率相似。所呈现的解剖分类从临床和手术角度来看都可能有用。

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