Attapattu M C
Department of Bacteriology and Mycology, Medical Research Institute, Colombo, Sri Lanka.
Mycopathologia. 1997;137(3):145-51. doi: 10.1023/a:1006819530825.
Chromoblastomycosis, a well-documented chronic fungal infection, represents a specific clinical entity with typical warty cutaneous nodules and a worldwide distribution. Although more prevalent in tropical and subtropical regions, only a few reports are available from Sri Lanka or from Asia. Five etiologic agents of chromoblastomycosis have been recognized worldwide. Of these the majority of infections have been caused by Fonsecaea pedrosoi. During the period from 1952 to 1962, only twelve culturally proven cases of this disease had been recorded from Sri Lanka. The fungus responsible was F. pedrosoi. The present report presents a study of the clinical and mycological features of 71 Sri Lankan patients with chromoblastomycosis for the 16-year period from 1978 to 1993. It documents three etiological agents. Culture identification was made in 69 cases. The three fungal species were Fonsecaea pedrosoi (64), Phialophora verrucosa (3) and a fungus compatible morphologically with F. compacta (2). The isolation of a fungus morphologically compatible with F. compacta is of significance since only 12 cases have been documented in the world's literature so far.
着色芽生菌病是一种有充分文献记载的慢性真菌感染，是一种具有典型疣状皮肤结节且分布于全球的特定临床实体。尽管在热带和亚热带地区更为常见，但来自斯里兰卡或亚洲的报道却很少。全世界已确认有五种引起着色芽生菌病的病原体。其中，大多数感染是由裴氏着色霉引起的。在1952年至1962年期间，斯里兰卡仅记录了12例经培养证实的该病病例。致病真菌为裴氏着色霉。本报告对1978年至1993年这16年间71例斯里兰卡着色芽生菌病患者的临床和真菌学特征进行了研究。报告记录了三种病原体。69例进行了培养鉴定。这三种真菌分别是裴氏着色霉（64例）、疣状瓶霉（3例）和一种形态上与紧密着色霉相符的真菌（2例）。分离出形态上与紧密着色霉相符的真菌具有重要意义，因为迄今为止世界文献中仅记载了12例。
