van Straten A, de Haan R J, Limburg M, Schuling J, Bossuyt P M, van den Bos G A
Department of Social Medicine, Academic Medical Center, University of Amsterdam, The Netherlands.
Stroke. 1997 Nov;28(11):2155-61. doi: 10.1161/01.str.28.11.2155.
In view of the growing therapeutic options in stroke, measurement of quality of life has become increasingly relevant as an outcome parameters. The Sickness Impact Profile (SIP) is one of the most widely used measures to assess quality of life. To overcome the major disadvantage of the SIP, its length, we constructed a short stroke adapted 30-item SIP version (SA-SIP30).
Data on the original SIP version were collected for 319 communicative patients at 6 months after stroke. The 12 subscales and the 136 items of the original SIP were reduced to 8 subscales with 30 items in a three step procedure, on the basis of relevancy and homogeneity. Reliability of the SA-SIP30 was evaluated by means of an analysis of homogeneity (Cronbach's alpha coefficient). Different types of validity were assessed: construct, clinical, and external validities.
Homogeneity of the SA-SIP30 was demonstrated by a high Cronbach's alpha (0.85). Principal component analyses revealed the same two dimensions as in the original SIP (a physical and a psychosocial dimension). The SA-SIP30 could explain 91% of the variation in scores of the original SIP in the same cohort of patients, and 89% in a different cohort. Furthermore, the SA-SIP30 was related to other functional health measures similar to how the original SIP was. We could demonstrate that the SA-SIP30 was able to distinguish patients with lacunar infarctions from patients with cortical or subcortical lesions.
We conclude that the SA-SIP30 is a feasible and clinimetrically sound measure to assess quality of life after stroke.
鉴于中风治疗选择的不断增加，生活质量测量作为一项结果参数变得越来越重要。疾病影响量表（SIP）是评估生活质量最广泛使用的方法之一。为克服SIP的主要缺点，即其篇幅过长，我们构建了一个简短的、适用于中风患者的30项SIP版本（SA - SIP30）。
收集了319名中风后6个月有交流能力患者的原始SIP版本数据。基于相关性和同质性，通过三步程序将原始SIP的12个分量表和136个项目缩减为8个分量表共30个项目。通过同质性分析（克朗巴赫α系数）评估SA - SIP30的信度。评估了不同类型的效度：结构效度、临床效度和外部效度。
SA - SIP30具有较高的克朗巴赫α系数（0.85），证明了其同质性。主成分分析揭示了与原始SIP相同的两个维度（身体维度和心理社会维度）。在同一组患者中，SA - SIP30能解释原始SIP分数变异的91%，在另一组患者中为89%。此外，SA - SIP30与其他功能健康测量指标的关系与原始SIP相似。我们能够证明SA - SIP30能够区分腔隙性梗死患者与皮质或皮质下病变患者。
我们得出结论，SA - SIP30是评估中风后生活质量的一种可行且在临床测量学上合理的方法。
