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下肢动脉重建中的血流动力学。I. 血流

Hemodynamics in arterial reconstructions of the lower limb. I. blood flow.

作者信息

Dedichen H

出版信息

Acta Chir Scand. 1976;142(3):213-20.

PMID:936949
Abstract

In order to establish normal and critical rates for peroperative, arterial blood flow, measurements were performed on 230 ileo-femoro-popliteal arteries subjected to reconstruction for atherosclerosis. Mean, basal blood flow after reconstruction was 134, 254 and 372 ml/min in the s. femoral, c. femoral and c. iliac arteries in vessels remaing open. These flow rates increased to a maximum of 375, 822 and 975 ml/min after intra-arterial injection of 40 mg papaverine. Flow rates were significantly lower in operations followed by early failure. In successfully reconstructed arteries, the mean, basal flow was restored to normal, but flow amplitude was still reduced, diastolic backflow was rarely seen and the flow-response to intra-arterial papaverine was significantly less than in normal arteries. Critical flow rates could not be defined but the frequency of primary failure increased significantly when basal blood flow after reconstruction was less than 100 ml/min or the papaverine induced flow was less than 200 ml/min. Preoperative blood flow was found to correlate well with the primary results of the operation while correlation with late results was less evident.

摘要

为了确定手术期间动脉血流的正常和临界速率,对230条因动脉粥样硬化而接受重建的髂股腘动脉进行了测量。在仍保持通畅的血管中,重建后股浅动脉、股总动脉和髂总动脉的平均基础血流分别为134、254和372毫升/分钟。动脉内注射40毫克罂粟碱后,这些血流速率分别增至最高375、822和975毫升/分钟。早期失败的手术中血流速率显著更低。在成功重建的动脉中,平均基础血流恢复正常,但血流幅度仍降低,舒张期逆流很少见,且对动脉内罂粟碱的血流反应明显小于正常动脉。无法确定临界血流速率,但当重建后的基础血流低于100毫升/分钟或罂粟碱诱导的血流低于200毫升/分钟时,原发性失败的频率显著增加。发现术前血流与手术的初步结果密切相关,而与远期结果的相关性则不太明显。

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