中性粒细胞趋化缺陷与高免疫球蛋白E血症——一种可逆性缺陷？
Defective neutrophil chemotaxis and hyperimmunoglobulinemia E-a reversible defect?
作者信息
Fontan G, Lorente F, Garcia Rodriguez M C, Ojeda J A
出版信息
Acta Paediatr Scand. 1976 Jul;65(4):509-11. doi: 10.1111/j.1651-2227.1976.tb04922.x.
Abstract
An eleven-month-old boy is presented with chronic atopic dermatitis and recurrent infections of the skin and respiratory tract, including subcutaneous abscesses. Immunological studies disclosed a neutrophil chemotactic defect, blood eosinophilia and serum hyper IgE. The clinical and analytical data are similar to those of patients previously dermatitis reversed the chemotatic defect, the blood eosinophilia and the clinical symptoms.
摘要
一名11个月大的男童患有慢性特应性皮炎，皮肤和呼吸道反复感染，包括皮下脓肿。免疫学研究发现存在中性粒细胞趋化缺陷、血液嗜酸性粒细胞增多和血清IgE升高。临床和分析数据与先前报道的患者相似。皮炎改善后，趋化缺陷、血液嗜酸性粒细胞增多和临床症状均有所缓解。
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