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阿尔茨海默病和血管性痴呆的高龄成年人基于人群样本的情景记忆功能。

Episodic memory functioning in population-based samples of very old adults with Alzheimer's disease and vascular dementia.

作者信息

Hassing L, Bäckman L

机构信息

Department of Psychology, Göteborg University, Sweden.

出版信息

Dement Geriatr Cogn Disord. 1997 Nov-Dec;8(6):376-83. doi: 10.1159/000106658.

Abstract

Population-based samples of normal old adults, patients with Alzheimer's disease (AD), and patients with vascular dementia (VaD) between 90 and 100 years of age were given a series of episodic memory tasks, assessing face recognition, word recall, and object recall. Results indicated (a) no group differences in those variables reflecting primary memory, and clear dementia-related deficits in secondary memory; (b) no differences between persons with AD and VaD in face recognition and object recall, and (c) an advantage of VaD patients compared with AD patients in word recall. It was suggested that the ability to transfer information from temporary to permanent storage may be particularly affected by a dementing disease. In addition, the selective AD-related deficit in word recall was interpreted in terms of a greater impairment of various language-related skills in AD compared with VaD.

摘要

选取了年龄在90至100岁之间的正常老年人、阿尔茨海默病(AD)患者和血管性痴呆(VaD)患者作为基于人群的样本,让他们完成一系列情景记忆任务,包括面部识别、单词回忆和物体回忆。结果表明:(a)在反映初级记忆的变量方面,各组之间没有差异,而在次级记忆方面存在明显的与痴呆相关的缺陷;(b)AD患者和VaD患者在面部识别和物体回忆方面没有差异;(c)在单词回忆方面,VaD患者比AD患者具有优势。研究表明,将信息从临时存储转移到永久存储的能力可能特别容易受到痴呆疾病的影响。此外,与VaD相比,AD患者在单词回忆方面存在与AD相关的选择性缺陷,这可以用AD患者各种语言相关技能受到的更大损害来解释。

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