Karlsson K A
Adv Exp Med Biol. 1976;71:15-25. doi: 10.1007/978-1-4614-4614-9_2.
Mass spectrometry of intact ganglioside derivatives has been shown to afford a specific information on type, number and sequence of sugars, as well as ceramide structure. This is illustrated here for a hematoside with N-glycolylneuraminic acid and a disialyldihexosylceramide. As shown elsewhere, this novel technique, needing only 10 micrograms for a spectrum, is generally applicable to all types of glycolipids, including complex blood group fucolipids.
完整神经节苷脂衍生物的质谱分析已被证明能提供有关糖的类型、数量和序列以及神经酰胺结构的特定信息。本文以含有N-羟乙酰神经氨酸的血型糖脂和二唾液酸二己糖神经酰胺为例进行说明。如其他地方所示，这种新技术只需10微克就能获得一张质谱图，通常适用于所有类型的糖脂，包括复杂血型岩藻糖脂。
