冠状动脉疾病中的血浆肝素中和活性。

Plasma heparin neutralizing activity in coronary artery disease.

作者信息

Dana B, Ellman L, Carvalho A, Daggett W M, Hutter A M

出版信息

Am J Cardiol. 1976 Jul;38(1):9-11. doi: 10.1016/0002-9149(76)90055-2.

Abstract

Platelets contain heparin neutralizing activity that is released into plasma after platelet aggregation. Increased amounts of plasma heparin neutralizing activity were found in patients with acute myocardial infarction, unstable angina pectoris and stable arteriographically confirmed coronary artery disease. Plasma heparin neutralizing activity levels provide additional evidence for a role of platelet aggregation in coronary artery disease.

摘要

血小板含有肝素中和活性，在血小板聚集后释放到血浆中。在急性心肌梗死、不稳定型心绞痛和经血管造影证实的稳定型冠状动脉疾病患者中，发现血浆肝素中和活性增加。血浆肝素中和活性水平为血小板聚集在冠状动脉疾病中的作用提供了额外证据。