Wainwright S P, Gould D
Department of Nursing Studies, King's College London.
J Adv Nurs. 1997 Nov;26(5):968-77. doi: 10.1046/j.1365-2648.1997.00451.x.
The problems of non-adherence with treatment in health care in general, and with medication adherence in particular, is an area with a voluminous and burgeoning literature. However, there appears to be no review of the literature on non-adherence with medications in organ transplant patients. This comprehensive review therefore considers literature on adherence in adult kidney, heart and liver transplantation. The particular problem of adherence in paediatric transplant patients is also addressed. This transplant research literature is then evaluated within the broader context of social science research on medication adherence. From the review it is apparent that there is an urgent need for research which examines the patient's beliefs about their illness and medicines. Such research is a precursor for rigorous nursing intervention studies which aim to promote adherence by being tailored to the patient's perceptions.
总体而言，医疗保健中不坚持治疗的问题，尤其是不坚持药物治疗的问题，是一个文献众多且不断涌现的领域。然而，似乎尚无关于器官移植患者不坚持药物治疗的文献综述。因此，本全面综述考虑了关于成人肾移植、心脏移植和肝移植中坚持治疗的文献。还探讨了儿科移植患者坚持治疗这一特殊问题。然后，在关于药物治疗依从性的社会科学研究这一更广泛背景下对该移植研究文献进行评估。从综述中可以明显看出，迫切需要开展研究，考察患者对自身疾病和药物的看法。此类研究是严格的护理干预研究的先导，这些干预研究旨在根据患者的认知进行调整，以促进治疗依从性。
