Oyuku Milton, Nshakira Nathan
Nexus International University, P. O. Box 70773 ClockTower, Kampala, Plot 105, Block 124, Ttamu, Mityana Municipality, Kampala, Uganda.
Kabale University, P.O Box 317, Plot 364 Block 3 Kikungiri Hill, Kabale Municipality, Kabale, Uganda.
BMC Health Serv Res. 2025 Jul 31;25(1):1010. doi: 10.1186/s12913-025-13076-y.
The study aimed to identify factors influencing compliance with chemotherapy handling and administration standard operation procedures (SOPs) among nurses and pharmacists at the Uganda Cancer Institute outpatient and pharmacy.
This descriptive cross -sectional study was conducted from May to July 2022 using self-administered questionnaires, interviews, and physical observations with a checklist. Data were entered into Excel and analyzed using STATA. Data was collected from every member of the population because it is small, accessible, and cooperative. Content analysis was used to quantify and analyze SOP Compliance among the participants.
The study involved 23 participants, including pharmacists and nurses handling chemotherapy. Among them, 22% held postgraduate qualifications, 17% had degrees, and 61% held diplomas. The group was 52% female and 48% male, with 65% being nurses and 35% pharmacists. Most participants (65%) had over four years of service, while 13% had three to four years or one to two years of service. Compliance with SOPs among nurses was 56%, while non-compliance was 44%. Among pharmacists, compliance was 53% and non-compliance was 47%.
Compliance was primarily influenced by individual factors, knowledge and attitudes. Age, education level, and years of service did not affect compliance. Occupational factors, facility availability and staff supervision, significantly influenced compliance. Organizational factors, training, communication with management, and management's commitment to health and safety, also impacted compliance. While organizational factors affected both individual and occupational factors, the latter two did not influence each other.
本研究旨在确定影响乌干达癌症研究所门诊和药房护士及药剂师遵守化疗处理和给药标准操作程序（SOPs）的因素。
本描述性横断面研究于2022年5月至7月进行，采用自填式问卷、访谈和带有检查表的实地观察。数据录入Excel并使用STATA进行分析。由于总体规模小、易于接触且配合度高，因此从每个人口中收集了数据。采用内容分析法对参与者的SOP合规情况进行量化和分析。
该研究涉及23名参与者，包括处理化疗的药剂师和护士。其中，22%拥有研究生学历，17%拥有本科学位，61%拥有文凭。该组中女性占52%，男性占48%，护士占65%，药剂师占35%。大多数参与者（65%）有超过四年的工作经验，而13%有三至四年或一至两年的工作经验。护士的SOP合规率为56%，不合规率为44%。药剂师的合规率为53%，不合规率为47%。
合规主要受个人因素、知识和态度的影响。年龄、教育水平和工作年限不影响合规情况。职业因素、设施可用性和员工监督对合规有显著影响。组织因素，如培训、与管理层的沟通以及管理层对健康和安全的承诺，也会影响合规情况。虽然组织因素影响个人和职业因素，但后两者之间互不影响。
