Khan M H, Khan I, Shah S H, Rashid Q
Research Centre, Ayub Medical College, Abbottabad, Pakistan.
J Environ Pathol Toxicol Oncol. 1995;14(2):117-20.
We measured blood lead level, hemoglobin, and urinary amino-levulinic acid (ALA) in industrial workers and in individuals exposed to vehicle smoke. Industrial workers and people exposed to traffic smoke had comparatively higher blood lead levels than the controls (p < 0.0001). Similarly, urinary ALA was 3.82 mg/dL in industrial subjects, 3.68 mg/dL in traffic-exposed people, and 0.8 mg/dL in control subjects (p < 0.001). The hemoglobin level was lower in the industrial group and in the traffic exposure group compared with the control group (p < 0.01). Traffic smoke-exposed persons, such as traffic police staff, had higher blood lead level than those handling lead material, Government Transport Service (GTS) workshop staff. The length of exposure showed no relationship with the lead levels. However, a positive correlation was observed between the duration of exposure and urinary ALA in both sample groups. The major signs and symptoms of the population studied included headache, generalized body pain, hypertension, and depression.
我们测量了产业工人和接触汽车尾气烟雾人群的血铅水平、血红蛋白以及尿中δ-氨基乙酰丙酸(ALA)含量。产业工人和接触交通烟雾人群的血铅水平相较于对照组更高(p < 0.0001)。同样,产业工人尿中ALA为3.82 mg/dL,接触交通烟雾人群为3.68 mg/dL,而对照组为0.8 mg/dL(p < 0.001)。与对照组相比,产业组和交通烟雾暴露组的血红蛋白水平更低(p < 0.01)。接触交通烟雾的人群,如交警工作人员,其血铅水平高于接触铅材料的人群,即政府运输服务(GTS)车间工作人员。暴露时长与铅水平无关联。然而,在两个样本组中,暴露时长与尿中ALA之间均观察到正相关。所研究人群的主要体征和症状包括头痛、全身疼痛、高血压和抑郁。