Soejima K, Nozaki M, Sasaki K, Takeuchi M, Negishi N
Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical College, Japan.
Ann Plast Surg. 1997 Nov;39(5):489-94. doi: 10.1097/00000637-199711000-00008.
From January 1994 to October 1995, 5 patients with congenital giant pigmented nevi were treated using artificial dermis with a secondary skin graft from the scalp. The nevus was excised in full thickness and the open wound was grafted with artificial dermis. About 3 weeks later, thin split-thickness skin grafting on the newly synthesized, dermis-like tissue was required. We chose the scalp as the donor of the secondary skin graft. Epithelialization of each donor site was completed within 1 week. In addition, the donor site was not complicated with alopecia or hypertrophic scars. Morbidity at the donor site was minimized and favorable tissue quality of the grafted skin was obtained. The clinical results revealed that the scalp was a favorable donor of a secondary skin graft for the treatment of giant pigmented nevus with artificial dermis.
1994年1月至1995年10月，对5例先天性巨色素痣患者采用人工真皮联合头皮二期植皮进行治疗。将痣完整切除，创面用人工真皮移植覆盖。约3周后，需在新合成的类似真皮组织上进行薄层皮片移植。我们选择头皮作为二期植皮的供区。每个供区在1周内完成上皮化。此外，供区未出现脱发或增生性瘢痕等并发症。供区的发病率降至最低，并获得了移植皮肤良好的组织质量。临床结果表明，头皮是采用人工真皮治疗巨色素痣二期植皮的理想供区。
