Yeates K O, Bornstein R A
Department of Pediatrics, Ohio State University, Children's Hospital, Columbus 43205, USA.
J Int Neuropsychol Soc. 1996 Sep;2(5):375-82. doi: 10.1017/s1355617700001442.
Neuropsychological deficits in Tourette's syndrome (TS) may be associated with learning disabilities. We examined the neuropsychological performance of 70 children with TS between the ages 6 and 18 years who were classified into four groups based on their pattern of performance on the Wide Range Achievement Test-Revised. The groups included three learning disability subtypes and a nonlearning disabled comparison group. The groups differed significantly on several measures in a comprehensive neuropsychological test battery. The pattern of differences was not entirely consistent with previous research, however, suggesting that neuropsychological correlates of learning disabilities may be influenced by the specific pathophysiology associated with TS. Thus, previous research on the neuropsychology of learning disability subtypes might not be generalizable to children with discrete neuropsychiatric disorders such as TS.
抽动秽语综合征(TS)中的神经心理学缺陷可能与学习障碍有关。我们对70名6至18岁的TS儿童的神经心理学表现进行了检查,这些儿童根据他们在《广泛成就测验修订版》中的表现模式被分为四组。这些组包括三种学习障碍亚型和一个非学习障碍对照组。在一个全面的神经心理学测试组中,这些组在几项测量指标上有显著差异。然而,差异模式并不完全与先前的研究一致,这表明学习障碍的神经心理学关联可能受与TS相关的特定病理生理学影响。因此,先前关于学习障碍亚型神经心理学的研究可能不适用于患有诸如TS等离散神经精神疾病的儿童。